Is convalescent plasma futile in COVID-19? A Bayesian re-analysis of the RECOVERY randomized controlled trial
Background: Randomized trials are generally performed from a frequentist perspective, which can conflate absence of evidence with evidence of absence.The RECOVERY trial evaluated convalescent plasma for patients hospitalized with coronavirus disease 2019 (COVID-19) and concluded that there was no evidence of an effect.Re-analysis from a Bayesian pe